![](https://bioreg.kyushu-u.ac.jp/labo/ged/wp/wp-content/uploads/2021/02/ESC_2-1.png)
Using mouse embryonic stem (ES) cells as a model, we aim to elucidate the regulatory mechanism of a phenomenon called transcriptional bursting using a novel experimental approach that combines genome editing technology, live imaging, and cell biology. We are also working on elucidating the molecular mechanism of cell-to-cell heterogeneity in gene expression levels in mouse ES cells.