第700回 生医研セミナー(多階層生体防御システム研究拠点)
免疫機構研究セミナー

下記の通り、Professor Gordon Brownによるセミナーを開催致します。皆様のご来聴を心より歓迎いたします。

演題

C-type lectin receptors and the control of immunity

演者

Professor Gordon Brown
Division of Applied Medicine Immunity
Section of Infection and Immunity
University of Aberdeen, UK

日時

2015年 11月12日(木) Nov. 12 (Thu), 2015
14:00~15:30

場所

九州大学 病院キャンパス内 生体防御医学研究所 本館1階 会議室
以下の地図の24番の建物になります。
(http://www.kyushu-u.ac.jp/access/map/hospital/hospital.html)

Seminar Room, Main Building 1F, Medical Institute of Bioregulation
No.24 on the following linked map.
(http://www.kyushu-u.ac.jp/access/map/hospital/hospital-e.html)

要旨

The last few decades has seen a tremendous increase in our understanding of the mechanisms underlying the development of protective anti-microbial immunity. Key among these discoveries is the identification of pattern recognition receptors (or PRRs) expressed by immune cells which recognise conserved microbial components, such as beta-glucans. Recognition of these structures by PRRs, particularly by members of the C-type lectin receptor (CLR) family, triggers intracellular signalling cascades that initiate a variety of cellular and inflammatory responses, and induce the development of pathogen specific adaptive immunity. We now understand that innate recognition by CLRs is essential for the development of protective antimicrobial immunity but there is also emerging evidence that the functions of these receptors play a role in homeostasis and autoimmunity. In this presentation, I will cover the recent developments in our understanding of the function and roles of these receptors.

連絡先

生体防御医学研究所 分子免疫学分野 山崎 晶
電話:092-642-4614