Our laboratory studies the mechanisms of epigenetic regulation of the mammalian genome and its role in human health. Epigenetics may be an unfamiliar word, but it describes the mechanisms regulating gene expression patterns during development without affecting the DNA sequence. Differentiated cells need to maintain their gene expression patterns through DNA replication and cell division, and this is also achieved by the epigenetic mechanisms. The molecular basis of epigenetics is chemical modifications of chromatin, and the entire modification state of a specific cell is called the epigenome. Epigenetics is an important theme in the post-genomic era and is a key to elucidate various biological phenomena and human diseases.What's New
- 2016.1102 The 26th Hot Spring Harbor International Symposium
- 2016.0513 PhD students Shirane and Maenohara get awards at the CSHA
- 2016.0403 Hanami (Cherry blossom viewing)
- 2016.0130 Commemorative ceremony for Prof. Sasaki
- 2016.0130 Commemorative lecture meeting for Prof. Sasaki
- 2016.0118 10th joint annual retreat of Epigenetics laboratories (Profs. Sasaki, Shinkai, Kakutani, Sado, Tachibana, and Saze's labs)
- 2016.0105 English website open.